How humans have shaped dogs’ brains

Dog brain structure varies across breeds and is correlated with specific behaviors, according to new research published in JNeurosci. These findings show how, by selectively breeding for certain behaviors, humans have shaped the brains of their best friends. Over several hundred years, humans have selectively bred dogs to express specific physical and behavioral characteristics. Erin Hecht … Read more

Mystery solved about the machines that move your genes

Fleets of microscopic machines toil away in your cells, carrying out critical biological tasks and keeping you alive. By combining theory and experiment, researchers have discovered the surprising way one of these machines, called the spindle, avoids slowdowns: congestion. The spindle divides chromosomes in half during cell division, ensuring that both offspring cells contain a … Read more

Novel math could bring machine learning to the next level

A team of Italian mathematicians, including one who is also a neuroscientist from the Champalimaud Centre for the Unknown (CCU), in Lisbon, Portugal, has shown that artificial vision machines can learn to recognize complex images spectacularly faster by using a mathematical theory that was developed 25 years ago by one of this new study’s co-authors. … Read more

Enhancing land carbon sink by carbon dioxide fertilization

Elevated atmospheric carbon dioxide concentration increases land carbon sink, partially offsetting carbon dioxide emissions from human activities such as fossil fuel, cement production, and land-use change. This process is known as carbon dioxide fertilization, playing a key role in climate change mitigation and sustainable development of human society. Quantifying the carbon dioxide fertilization on the … Read more

Impact of climate change on global banana yields revealed

Bananas are recognised as the most important fruit crop – providing food, nutrition and income for millions in both rural and urban areas across the globe. While many reports have looked at the impact of climate change on agricultural production, the effect rising temperatures and changing rainfall has on crucial tropical crops such as the … Read more

Unique Neoproterozoic carbon isotope excursions sustained by coupled evaporite dissolution and pyrite burial

The earliest large animal fossils lived in deep marine, oxygenated environments, now in central England (Leicestershire) and Newfoundland, following a cold spell about 575 million years ago, but within about 30-40 million years, the strange lifeforms gave way to more recognisable animals (worms, coral-like animals, sponges, etc.). What drove this change? A new UCL-led study … Read more

Novel molecules designed by artificial intelligence in 21 days are validated in mice

Insilico Medicine, a global leader in artificial intelligence for drug discovery, today announced the publication of a paper titled, “Deep learning enables rapid identification of potent DDR1 kinase inhibitors,” in Nature Biotechnology. The paper describes a timed challenge, where the new artificial intelligence system called Generative Tensorial Reinforcement Learning (GENTRL) designed six novel inhibitors of DDR1, … Read more

People believe achieving environmental sustainability could hinder quality of life

Attempts such as the U.S. ‘Green New Deal’ to create a more environmentally, economically, and socially sustainable world face a major challenge – people are sceptical you can achieve all three. And they believe that targeting environmental outcomes like climate change and pollution comes at a cost to efforts to improve their quality of life. … Read more

Map of broken brain networks shows why people lose speech in language-based dementia

For the first time, Northwestern Medicine scientists have pinpointed the location of dysfunctional brain networks that lead to impaired sentence production and word finding in primary progressive aphasia (PPA), a form of dementia in which patients often lose their language rather than their memory or thought process. With this discovery, the scientists have drawn a … Read more