Using gold to read cancer’s messages

A novel blood test that uses gold nanoparticles to detect cancer has also been shown to identify signals released by cancer cells which could result in earlier diagnosis and better treatment. New research has revealed the nanotechnology developed by University of Queensland scientists can detect and monitor extracellular vesicles (EVs) in the bloodstream. Australian Institute … Read more Using gold to read cancer’s messages

Human gut-in-a-dish model helps define ‘leaky gut,’ and outline a pathway to treatment

Once a vague scapegoat for a variety of ills, increasing evidence suggests a condition known as “leaky gut” – in which microbes and other molecules seep out of the intestines – may be more common, and more harmful, than previously thought. Leaky gut is most often experienced by older people, patients with cancers or other … Read more Human gut-in-a-dish model helps define ‘leaky gut,’ and outline a pathway to treatment

Tiny magnetic structures enhance medical science

Small magnetic objects, which have been used successfully in technological applications such as data storage, are showing promise in the biomedical field. Magnetic nanostructures have interesting properties that enhance novel applications in medical diagnosis and allow the exploration of new therapeutic techniques. In this week’s Applied Physics Review, by AIP Publishing, researchers review the state of … Read more Tiny magnetic structures enhance medical science

UofT researchers find: Most engineered nanoparticles enter tumours through cells, not between them

The prevailing theory in cancer nanomedicine — an approach that enables more targeted therapies than standard chemotherapy — has been that nanoparticles mainly diffuse passively into tumours through tiny gaps between cells in the endothelium, which lines the inner wall of blood vessels that support tumour growth. The researchers previously showed that less than one per … Read more UofT researchers find: Most engineered nanoparticles enter tumours through cells, not between them

Penn shows giving entire course of radiation treatment in less than a second is feasible

Cancer patients may one day be able to get their entire course of radiation therapy in less than a second rather than coming in for treatment over the course of several weeks, and researchers in the Abramson Cancer Center of the University of Pennsylvania have taken the first steps toward making it a reality. In … Read more Penn shows giving entire course of radiation treatment in less than a second is feasible

New imaging system and artificial intelligence algorithm accurately identify brain tumors

Published in Nature Medicine on January 6, the study examined the diagnostic accuracy of brain tumor image classification through machine learning, compared with the accuracy of pathologist interpretation of conventional histologic images. The results for both methods were comparable: the AI-based diagnosis was 94.6% accurate, compared with 93.9% for the pathologist-based interpretation. The imaging technique, stimulated Raman … Read more New imaging system and artificial intelligence algorithm accurately identify brain tumors

Revolutionary treatment cures beloved family pet

A novel immunotherapy treatment has saved family dog Griffin from a rare type of cancer, thanks to collaborative research at The University of Queensland. The Rottweiler was diagnosed with T cell lymphoma in December 2017 and given three months to live. UQ’s Dr Rachel Allavena and her PhD student, veterinarian Dr Annika Oksa, enrolled Griffin … Read more Revolutionary treatment cures beloved family pet

Artificial intelligence identifies previously unknown features associated with cancer recurrence

Artificial intelligence (AI) technology developed by the RIKEN Center for Advanced Intelligence Project (AIP) in Japan has successfully found features in pathology images from human cancer patients, without annotation, that could be understood by human doctors. Further, the AI identified features relevant to cancer prognosis that were not previously noted by pathologists, leading to a … Read more Artificial intelligence identifies previously unknown features associated with cancer recurrence

New tool reveals DNA structures that influence disease

Disruption of certain DNA structures – called topologically associating domains, or TADs – is linked with the development of disease, including some cancers. With its newly created algorithm that quickly locates and helps elucidate the complex functions of TADs, an international team of researchers is making it easier to study these important structures and help … Read more New tool reveals DNA structures that influence disease

A way to ‘fingerprint’ human cells

Researchers say a new method to analyse data from individual human cells could be a step-change for diagnosing some of the most devastating diseases, including cancer and autoimmune disease. By combining single cell analysis techniques with machine learning algorithms, a team led by researchers at the Garvan Institute of Medical Research has developed a method … Read more A way to ‘fingerprint’ human cells