HIV: overwhelming the enemy from the start

1.7 million That’s how many people are infected with the human immunodeficiency virus (HIV) each year worldwide – 1.7 million people condemned to lifelong antiretroviral therapy (ART) or who risk developing fatal AIDS. Out of the 37.9 million people living with HIV (PLWH), 22.3 million have access to ART, allowing them to have an almost … Read more

Malaria discovery could lead to better HIV and lupus treatments

A discovery about how the immune system responds to malaria infection could lead to better treatments for hepatitis C, HIV and lupus, say Australian researchers. The research team showed, in laboratory models, that strong inflammatory signals caused by malaria infection activate molecules that trigger the production of highly potent antibodies to fight the disease. The … Read more

New research explains how HIV avoids getting ZAPped

Humans have evolved dynamic defense mechanisms against the viruses that seek to infect our bodies – proteins that specialize in identifying, capturing and destroying the genetic material that viruses try to sneak into our cells. A new study, scheduled to publish the week of Nov. 11 in Proceedings of the National Academy of Sciences, now reveals … Read more

HIV eliminated from the genomes of living animals

In a major collaborative effort, researchers at the Lewis Katz School of Medicine at Temple University and the University of Nebraska Medical Center (UNMC) have for the first time eliminated replication-competent HIV-1 DNA – the virus responsible for AIDS – from the genomes of living animals. The study, reported online July 2 in the journal Nature … Read more

‘Striking’ Differences in Rates of HIV/AIDS within African Nations

Despite the rapid scale-up of antiretroviral therapy (ART) since 2000, HIV/AIDS is still the most common cause of death in sub-Saharan Africa, according to data from the Global Burden of Disease. A new scientific paper reveals striking variation in HIV prevalence at provincial and district levels. The paper, published in Nature, provides precise geographic estimates … Read more