Human gut-in-a-dish model helps define ‘leaky gut,’ and outline a pathway to treatment

Once a vague scapegoat for a variety of ills, increasing evidence suggests a condition known as “leaky gut” – in which microbes and other molecules seep out of the intestines – may be more common, and more harmful, than previously thought. Leaky gut is most often experienced by older people, patients with cancers or other … Read more Human gut-in-a-dish model helps define ‘leaky gut,’ and outline a pathway to treatment

Phage therapy shows promise for alcoholic liver disease

Bacteriophages (phages) are viruses that specifically destroy bacteria. In the early 20th century, researchers experimented with phages as a potential method for treating bacterial infections. But then antibiotics emerged and phages fell out of favor. With the rise of antibiotic-resistant infections, however, researchers have renewed their interest in phage therapy. In limited cases, patients with … Read more Phage therapy shows promise for alcoholic liver disease

Big news for Irritable Bowel Syndrome patients

This is big news for Irritable Bowel Syndrome (IBS) patients: 11 percent of the world’s population suffers from IBS, but the fight against chronic pain has taken a major step forward with scientists identifying receptors in the nervous system which cause the condition in the hope of developing effective treatments. Flinders University researchers at SAHMRI … Read more Big news for Irritable Bowel Syndrome patients

Pitt first to grow genetically engineered mini livers to study disease and therapeutics

Researchers at the University of Pittsburgh School of Medicine are the first to grow genetically modified miniature human livers in the laboratory, to emulate human liver disease progression and test therapeutics. In a proof-of-concept paper published today in Cell Metabolism, Pitt researchers chronicle how they transformed genetically engineered human cells into functional, 3D liver tissue … Read more Pitt first to grow genetically engineered mini livers to study disease and therapeutics